来源：本站原创 发布时间：2020-02-26
日前，和信医院基因精准医疗研究院和国际知名遗传学家李修庆博士在美国《科学》杂志发表署名文章《命名建议：用CORS（传染性不透明肺呼吸系统综合征）和CORS-CoV（其致病病毒）作为COVID-19和SARS-CoV-2的通用名称》。
《科学》杂志是美国科学促进会出版的一份学术期刊，为全世界最权威的学术期刊之一。该杂志于1880年由爱迪生投资1万美元创办，于1894年成为美国最大的科学团体“美国科学促进会”（American Association for the Advancement of Science ，AAAS)的官方刊物。全年共51期，为周刊，全球发行量超过150万份。2018年12月，世界品牌实验室发布《2018世界品牌500强》榜单，《科学》排名第383。
李修庆博士早年在法国巴斯德研究院（Institut Pasteur）和法国南巴黎大学（Universite de Paris-Sud）留学并荣获法国国家博士学位，先后在法国国家自然科学研究中心任分子遗传学副研究员、北京大学生物系任遗传学副教授和博士生导师、南巴黎第六大学和巴黎第11大学联合专业的遗传学特邀教授、美国普渡大学访问教授、加拿大农业和农业食品部分子遗传学研究员。
基因精准医疗研究院是和信医院正在筹建的二期项目，建成后将进一步提高和信医院对疾病的研究、诊断和治疗水平。此次在《科学》杂志发表的署名文章全文（英文和中文翻译）如下：
将CORS和CORS-CoV做为新冠状病毒肺炎及其病毒名称的建议翻译自：Xiu-Qing Li, Vinson F. Lee, Ping Zhang, Xiang Gao, and Weiliang Xin (2020) RE: A naming proposal: Use Contagious Opaque-lung Respiratory Syndrome (CORS) and its viruses (CORS-CoV) as common names for COVID-19 and SARS-CoV-2. SCIENCE,eLetters 22 February 2020.
https://science.sciencemag.org/content/367/6480/836/tab-e-letters
RE：命名建议：用CORS（传染性不透明肺呼吸系统综合征）和CORS-CoV（其致病病毒）作为COVID-19和SARS-CoV-2的通用名称
Xiu-Qing Li （李修庆）, Vinson F. Lee, Ping Zhang（张平）,
Xiang Gao （高翔）, Weiliang Xin （信维亮）
最近在中国地区爆发的冠状病毒流行性传染病及其致病新病毒（1）在国际上的英文命名引起了学术界的广泛关注，并在一定程度上有名词混乱（2）。
该疾病最初命名为"武汉肺炎"(Wuhan pneumonia)（3、4）或"新冠状病毒肺炎”(Novel Coronavirus–Infected Pneumonia, NCIP）(5）。而后，世界卫生组织（WHO）将该疾病改名为COVID-19（6），但这个名称缺少对病症针对性的描述。所有这些对这次时疫疾病的名称都与前两次爆发的严重急性呼吸系统综合症（SARS，非典）和中东呼吸系统综合症（MERS）的名称并不相似，而且没有提及疾病关键性的症状特征，在命名上缺乏一致性和连贯性。
开初时，本次流行的冠状病毒被称为"2019-nCoV"（7），与先前两次爆发的冠状病毒SARS-CoV和MERS-CoV的命名方式很不相同。国际病毒分类委员会冠状病毒研究小组（CSG）随后又将2019年的新冠状病毒“2019-nCoV”命名为"SARS-CoV-2"，其依据是遗传进化系统的分组特点，并没考虑其病毒是否致病及疾病表现特征症状（8）。对此，世界卫生组织（WHO）也表示了关注，担心SARS-CoV-2这个名字看起来像非典，很可能会对2003年受非典疫情严重影响的地区的人们造成误解和不必要的恐惧（2）。其实，不管在遗传进化系统如何分组，对广大的公众和医生们而言，病毒病原体的通用名称最好是能反映出一些这种病毒引起的疾病特征症状。
这此疫情爆发出来的特点是，病毒有高度传染性，并会导致出现不透明肺这类症状（5）。比如，钻石公主号游轮（Diamond Princess cruise ship）很可能是由一名患者的冠状病毒逐步感染了 624 人（截至 2020 年 2 月 19 日）。相反，MERS-CoV病毒却不容易在人与人之间传播（9）。对于本次2019年新冠状病毒肺炎感染病患者，借助CT扫描，发现其特征症状是病人肺部表现为不透明的磨玻璃状（5）。按照非典SARS（或SARS-CoV为其致病病毒）和中东呼吸综合征MERS（或MERS-CoV为其致病病毒）的命名方式，我们建议将这种新疾病命名为"传染性不透明肺呼吸系统综合症（CORS）"，并将其致病冠状病毒命名为"CORS-CoV"。
作者：
Xiu-Qing Li （李修庆）加拿大农业和农业食品部弗雷德瑞克顿科研中心
Vinson F. Lee， 加拿大皇后大学商学院
Ping Zhang（张平）, 成都双流天地同光研究院
Xiang Gao （高翔）, 青岛大学附属医院变态（过敏）反应科
Weiliang Xin （信维亮）（山东寿光）精准医疗研究院、寿光和信医院
联系作者: Xiu-Qing.Li@Canada.Ca; Xiuqing.Li@yahoo.com; lixiuqing2008@gmail.com
SCIENCE eLetters, 22th February 2020
https://science.sciencemag.org/content/367/6480/836/tab-e-letters
RE: A naming proposal: Use Contagious Opaque-lung Respiratory Syndrome (CORS) and its viruses (CORS-CoV) as common names for COVID-19 and SARS-CoV-2
· Xiu-Qing Li, Research Scientist,Fredericton Research and Development Centre, Agriculture and Agri-Food Canada, 850 Lincoln Road, Fredericton, NB, E3B 4Z7 Canada
· Other Contributors:
Vinson F. Lee, Student,Smith School of Business, Queen’s University, Goodes Hall, Kingston, Ontario, K7L 3N6 Canada
o Ping Zhang, Research Scientist, Tianditongguang Research Institute, 777 4th Section of Huafu Road, Shuangliu District, Chengdu City, 610200 P. R. China
Xiang Gao, Medical Doctor, Department of Allergy, The Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao City, 266003 P. R. China
Weiliang Xin, Medical Doctor, Hexin Hospital, Precision Medicine Academy, 4438 Jianxin Road, Shouguang, Shandong, 262700 P.R. China
(22 February 2020)
“The coronavirus epidemic” and “the novel virus” described in Robert F. Service’s article (1) have been through chaotic naming processes (2).
The disease was originally named “Wuhan pneumonia”(3, 4) or “Novel Coronavirus–Infected Pneumonia (NCIP)”(5). The World Health Organization (WHO) renamed the disease to COVID-19 (6), which, however, lacks a description of symptoms. These names do not imply any similar conventions to SARS for the Severe Acute Respiratory Syndrome and MERS for the Middle East Respiratory Syndrome, two previous coronavirus outbreaks.
The causal virus of this coronavirus outbreak was called “2019-nCoV” (7), a different naming style from the two previous coronaviruses SARS-CoV and MERS-CoV. The Coronavirus Study Group (CSG) of the International Committee on Taxonomy of Viruses then named this 2019 new pathogen “SARS-CoV-2” based on phylogenetic grouping with no consideration of disease (8). However, WHO concerns that the terms may create unnecessary fear for some populations that were seriously affected by the SARS outbreak in 2003 (2). Regardless of phylogenetic positions, it is more convenient for the public and medical doctors if a viral pathogen has a common name with certain association with symptoms.
This new outbreak is characterized by being highly contagious and resulting in opaque-lung (5). For example, starting from a single patient, 624 people were infected by the coronavirus (by February 19, 2020) on the Diamond Princess cruise ship, whereas MERS-CoV did not spread easily from person-to-person (9). For the symptoms, the hallmark of this 2019 new pneumonia is the lung ground-glass opacity in CT scans (5). Along the same naming style of SARS (or SARS-CoV for its causal virus) and MERS (or MERS-CoV for its causal virus), we propose to name this new disease as “Contagious Opaque-lung Respiratory Syndrome (CORS)” and its causal coronavirus as “CORS-CoV”.
REFERENCES AND NOTES
1. R. F. Service, Coronavirus epidemic snarls science worldwide. Science 367, 836-837 (2020).
2. M. Enserink, Update: ‘A bit chaotic.’ Christening of new coronavirus and its disease name create confusion. Science, 10.1126/science.abb2806 (2020).
3. J. F.-W. Chan et al., A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. The Lancet 395, 514-523 (2020).
4. S. Jiang, S. Xia, T. Ying, L. Lu, A novel coronavirus (2019-nCoV) causing pneumonia-associated respiratory syndrome. Cellular and Molecular Immunology, https://doi.org/10.1038/s41423-41020-40372-41424 (2020).
5. D. Wang et al., Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China. JAMA, doi:10.1001/jama.2020.1585 (2020).
6.WHO. (World Health Organization, https://www.who.int/docs/default-source/coronaviruse/situation-reports/2..., 2020).
7. WHO. (World Health Organization https://www.who.int/publications-detail/the-first-few-x-(ffx)-cases-and-contact-investigation-protocol-for-2019-novel-coronavirus-(2019-ncov)-infection, 2020).
8. A. E. Gorbalenya et al., Severe acute respiratory syndrome-related coronavirus: The species and its viruses – a statement of the Coronavirus Study Group. bioRxiv preprint doi: https://doi.org/10.1101/2020.02.07.937862, (2020).
9. L. Pocock, M. Rezaeian, Virology vigilance - an update on MERS and viral mutation and epidemiology for family doctors. World Family Medicine Journal: Incorporating the Middle East Journal of Family Medicine 99, 1-8.
Competing interests: The authors declare no competing interests.
Corresponding author: Xiu-Qing.Li@Canada.Ca; Xiuqing.Li@yahoo.com; lixiuqing2008@gmail.com
Competing Interests: None declared.和信医院基因精准医疗研究院在《科学》杂志就新冠肺炎病毒发表署名文章
寿光和信医院 2月26日
日前，和信医院基因精准医疗研究院和国际知名遗传学家李修庆博士在美国《科学》杂志发表署名文章《命名建议：用CORS（传染性不透明肺呼吸系统综合征）和CORS-CoV（其致病病毒）作为COVID-19和SARS-CoV-2的通用名称》。
《科学》杂志是美国科学促进会出版的一份学术期刊，为全世界最权威的学术期刊之一。该杂志于1880年由爱迪生投资1万美元创办，于1894年成为美国最大的科学团体“美国科学促进会”（American Association for the Advancement of Science ，AAAS)的官方刊物。全年共51期，为周刊，全球发行量超过150万份。2018年12月，世界品牌实验室发布《2018世界品牌500强》榜单，《科学》排名第383。
李修庆博士早年在法国巴斯德研究院（Institut Pasteur）和法国南巴黎大学（Universite de Paris-Sud）留学并荣获法国国家博士学位，先后在法国国家自然科学研究中心任分子遗传学副研究员、北京大学生物系任遗传学副教授和博士生导师、南巴黎第六大学和巴黎第11大学联合专业的遗传学特邀教授、美国普渡大学访问教授、加拿大农业和农业食品部分子遗传学研究员。
基因精准医疗研究院是和信医院正在筹建的二期项目，建成后将进一步提高和信医院对疾病的研究、诊断和治疗水平。此次在《科学》杂志发表的署名文章全文（英文和中文翻译）如下：
将CORS和CORS-CoV做为新冠状病毒肺炎及其病毒名称的建议翻译自：Xiu-Qing Li, Vinson F. Lee, Ping Zhang, Xiang Gao, and Weiliang Xin (2020) RE: A naming proposal: Use Contagious Opaque-lung Respiratory Syndrome (CORS) and its viruses (CORS-CoV) as common names for COVID-19 and SARS-CoV-2. SCIENCE,eLetters 22 February 2020.
https://science.sciencemag.org/content/367/6480/836/tab-e-letters
RE：命名建议：用CORS（传染性不透明肺呼吸系统综合征）和CORS-CoV（其致病病毒）作为COVID-19和SARS-CoV-2的通用名称
Xiu-Qing Li （李修庆）, Vinson F. Lee, Ping Zhang（张平）,
Xiang Gao （高翔）, Weiliang Xin （信维亮）
最近在中国地区爆发的冠状病毒流行性传染病及其致病新病毒（1）在国际上的英文命名引起了学术界的广泛关注，并在一定程度上有名词混乱（2）。
该疾病最初命名为"武汉肺炎"(Wuhan pneumonia)（3、4）或"新冠状病毒肺炎”(Novel Coronavirus–Infected Pneumonia, NCIP）(5）。而后，世界卫生组织（WHO）将该疾病改名为COVID-19（6），但这个名称缺少对病症针对性的描述。所有这些对这次时疫疾病的名称都与前两次爆发的严重急性呼吸系统综合症（SARS，非典）和中东呼吸系统综合症（MERS）的名称并不相似，而且没有提及疾病关键性的症状特征，在命名上缺乏一致性和连贯性。
开初时，本次流行的冠状病毒被称为"2019-nCoV"（7），与先前两次爆发的冠状病毒SARS-CoV和MERS-CoV的命名方式很不相同。国际病毒分类委员会冠状病毒研究小组（CSG）随后又将2019年的新冠状病毒“2019-nCoV”命名为"SARS-CoV-2"，其依据是遗传进化系统的分组特点，并没考虑其病毒是否致病及疾病表现特征症状（8）。对此，世界卫生组织（WHO）也表示了关注，担心SARS-CoV-2这个名字看起来像非典，很可能会对2003年受非典疫情严重影响的地区的人们造成误解和不必要的恐惧（2）。其实，不管在遗传进化系统如何分组，对广大的公众和医生们而言，病毒病原体的通用名称最好是能反映出一些这种病毒引起的疾病特征症状。
这此疫情爆发出来的特点是，病毒有高度传染性，并会导致出现不透明肺这类症状（5）。比如，钻石公主号游轮（Diamond Princess cruise ship）很可能是由一名患者的冠状病毒逐步感染了 624 人（截至 2020 年 2 月 19 日）。相反，MERS-CoV病毒却不容易在人与人之间传播（9）。对于本次2019年新冠状病毒肺炎感染病患者，借助CT扫描，发现其特征症状是病人肺部表现为不透明的磨玻璃状（5）。按照非典SARS（或SARS-CoV为其致病病毒）和中东呼吸综合征MERS（或MERS-CoV为其致病病毒）的命名方式，我们建议将这种新疾病命名为"传染性不透明肺呼吸系统综合症（CORS）"，并将其致病冠状病毒命名为"CORS-CoV"。
作者：
Xiu-Qing Li （李修庆）加拿大农业和农业食品部弗雷德瑞克顿科研中心
Vinson F. Lee， 加拿大皇后大学商学院
Ping Zhang（张平）, 成都双流天地同光研究院
Xiang Gao （高翔）, 青岛大学附属医院变态（过敏）反应科
Weiliang Xin （信维亮）（山东寿光）精准医疗研究院、寿光和信医院
联系作者: Xiu-Qing.Li@Canada.Ca; Xiuqing.Li@yahoo.com; lixiuqing2008@gmail.com
SCIENCE eLetters, 22th February 2020
https://science.sciencemag.org/content/367/6480/836/tab-e-letters
RE: A naming proposal: Use Contagious Opaque-lung Respiratory Syndrome (CORS) and its viruses (CORS-CoV) as common names for COVID-19 and SARS-CoV-2
· Xiu-Qing Li, Research Scientist,Fredericton Research and Development Centre, Agriculture and Agri-Food Canada, 850 Lincoln Road, Fredericton, NB, E3B 4Z7 Canada
· Other Contributors:
Vinson F. Lee, Student,Smith School of Business, Queen’s University, Goodes Hall, Kingston, Ontario, K7L 3N6 Canada
o Ping Zhang, Research Scientist, Tianditongguang Research Institute, 777 4th Section of Huafu Road, Shuangliu District, Chengdu City, 610200 P. R. China
Xiang Gao, Medical Doctor, Department of Allergy, The Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao City, 266003 P. R. China
Weiliang Xin, Medical Doctor, Hexin Hospital, Precision Medicine Academy, 4438 Jianxin Road, Shouguang, Shandong, 262700 P.R. China
(22 February 2020)
“The coronavirus epidemic” and “the novel virus” described in Robert F. Service’s article (1) have been through chaotic naming processes (2).
The disease was originally named “Wuhan pneumonia”(3, 4) or “Novel Coronavirus–Infected Pneumonia (NCIP)”(5). The World Health Organization (WHO) renamed the disease to COVID-19 (6), which, however, lacks a description of symptoms. These names do not imply any similar conventions to SARS for the Severe Acute Respiratory Syndrome and MERS for the Middle East Respiratory Syndrome, two previous coronavirus outbreaks.
The causal virus of this coronavirus outbreak was called “2019-nCoV” (7), a different naming style from the two previous coronaviruses SARS-CoV and MERS-CoV. The Coronavirus Study Group (CSG) of the International Committee on Taxonomy of Viruses then named this 2019 new pathogen “SARS-CoV-2” based on phylogenetic grouping with no consideration of disease (8). However, WHO concerns that the terms may create unnecessary fear for some populations that were seriously affected by the SARS outbreak in 2003 (2). Regardless of phylogenetic positions, it is more convenient for the public and medical doctors if a viral pathogen has a common name with certain association with symptoms.
This new outbreak is characterized by being highly contagious and resulting in opaque-lung (5). For example, starting from a single patient, 624 people were infected by the coronavirus (by February 19, 2020) on the Diamond Princess cruise ship, whereas MERS-CoV did not spread easily from person-to-person (9). For the symptoms, the hallmark of this 2019 new pneumonia is the lung ground-glass opacity in CT scans (5). Along the same naming style of SARS (or SARS-CoV for its causal virus) and MERS (or MERS-CoV for its causal virus), we propose to name this new disease as “Contagious Opaque-lung Respiratory Syndrome (CORS)” and its causal coronavirus as “CORS-CoV”.
REFERENCES AND NOTES
1. R. F. Service, Coronavirus epidemic snarls science worldwide. Science 367, 836-837 (2020).
2. M. Enserink, Update: ‘A bit chaotic.’ Christening of new coronavirus and its disease name create confusion. Science, 10.1126/science.abb2806 (2020).
3. J. F.-W. Chan et al., A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. The Lancet 395, 514-523 (2020).
4. S. Jiang, S. Xia, T. Ying, L. Lu, A novel coronavirus (2019-nCoV) causing pneumonia-associated respiratory syndrome. Cellular and Molecular Immunology, https://doi.org/10.1038/s41423-41020-40372-41424 (2020).
5. D. Wang et al., Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China. JAMA, doi:10.1001/jama.2020.1585 (2020).
6.WHO. (World Health Organization, https://www.who.int/docs/default-source/coronaviruse/situation-reports/2..., 2020).
7. WHO. (World Health Organization https://www.who.int/publications-detail/the-first-few-x-(ffx)-cases-and-contact-investigation-protocol-for-2019-novel-coronavirus-(2019-ncov)-infection, 2020).
8. A. E. Gorbalenya et al., Severe acute respiratory syndrome-related coronavirus: The species and its viruses – a statement of the Coronavirus Study Group. bioRxiv preprint doi: https://doi.org/10.1101/2020.02.07.937862, (2020).
9. L. Pocock, M. Rezaeian, Virology vigilance - an update on MERS and viral mutation and epidemiology for family doctors. World Family Medicine Journal: Incorporating the Middle East Journal of Family Medicine 99, 1-8.
Competing interests: The authors declare no competing interests.
Corresponding author: Xiu-Qing.Li@Canada.Ca; Xiuqing.Li@yahoo.com; lixiuqing2008@gmail.com
Competing Interests: None declared.
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